Thermo Fisher Scientific PTP1B Recombinant Rabbit Monoclonal Antibody (1G3)
PTP1B 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA538341
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1G3 |
| Immunogen | A synthesized peptide derived from human PTP1B (amino acids 381–395) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898256 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that regulates the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK, thereby inactivating its kinase activity. PTP1B plays roles in CKII- and p60c-src-induced signaling cascades and regulates EFNA5-EPHA3 signaling, influencing cell reorganization and repulsion. It also modulates hepatocyte growth factor receptor (MET) signaling through dephosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-38341_PTP1B_P18031-1_Rabbit.svg, MA5-38341_PTP1B_P18031-1_Rabbit_PDP.jpeg)
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