Thermo Fisher Scientific FNTB Recombinant Rabbit Monoclonal Antibody (5H4)
Thermo Fisher Scientific의 FNTB Recombinant Rabbit Monoclonal Antibody (5H4)는 인간 및 랫트 반응성을 가진 재조합 단일클론 항체입니다. Western blot, IHC, IP에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:200–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H4 |
| Immunogen | A synthesized peptide derived from human FNTB (UniProt ID: P49356-1, antigen range: 26–41) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898254 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
Eukaryotic cells contain three types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) to C-terminal cysteine residues of various proteins. These posttranslational modifications enable membrane localization of proteins lacking transmembrane domains.
CAAX farnesyltransferase (FTase) transfers a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins ending in the CAAX box. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) is located on chromosome 14q23–q24.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: MA5-38339_FNTB_P49356-1_Rabbit.svg, MA5-38339_FNTB_P49356-1_Rabbit_PDP.jpeg)
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