Thermo Fisher Scientific CaMKK alpha Polyclonal Antibody
CaMKK alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, Human에 반응하고 Mouse 및 Rat에도 예측 반응합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 455 and 505 of human calcium/calmodulin-dependent protein kinase kinase 1, alpha (CaMKKα) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, predicted to react with Mouse and Rat
Target Information
CAMKK1 (CaMKKα) belongs to the serine/threonine protein kinase family and the Ca²⁺/calmodulin-dependent protein kinase subfamily.
It is a component of the nuclear factor of activated T cells (NFAT) DNA-binding transcription complex, which regulates inducible gene transcription during immune responses.
CAMKK1 functions as a molecular target for immunosuppressive drugs such as cyclosporin A.
Five transcript variants encoding distinct isoforms have been identified, which may regulate the inducible expression of different cytokine genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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