Thermo Fisher Scientific IL-2 Polyclonal Antibody
고양이 IL-2 단백질에 특이적인 Rabbit Polyclonal 항체로, WB, ELISA, IP에 적합합니다. Protein A로 정제된 Lyophilized 형태이며, 장기보관 시 -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 202-401-B95x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-2 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:20,000 |
| Immunoprecipitation (IP) | 1:500–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Cat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein raised in yeast corresponding to 134 amino acids of mature cat IL-2. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This antibody is specific for cat IL-2 protein. A BLAST analysis suggests:
- 100% homology with cat IL-2
- 90% homology with Northern elephant seal and gray seal IL-2
Cross-reactivity with IL-2 from other species has not been determined.
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine essential for:
- Proliferation of activated T cells
- Differentiation of B cells, NK cells, monocytes, and macrophages
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex sharing its gamma chain with IL-4 and IL-7.
In mature thymocytes, IL-2 gene expression is monoallelic, representing a unique regulatory mechanism.
Disruption of IL-2-like genes in mice leads to ulcerative colitis-like disease, indicating its critical role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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