Thermo Fisher Scientific Endoglin/CD105 (Angiogenesis Marker) Monoclonal Antibody (ENG/1621)
Endoglin/CD105 단일클론 항체로 혈관신생 마커 연구에 적합. 인간 및 다양한 종에 반응. ICC, Flow, ELISA 등 다양한 응용 가능. 비결합형 액상 형태로 안정적이며, Protein A/G 정제. 연구용으로만 사용.
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Thermo Fisher Scientific Endoglin/CD105 (Angiogenesis Marker) Monoclonal Antibody (ENG/1621)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Functional Assay | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Horse, Human, Non-human primate, Pig, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ENG/1621 |
| Immunogen | Recombinant extracellular fragment of human Endoglin protein (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD105, also known as Endoglin, is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, indicating its role as a proliferation-associated endothelial marker. CD105 binds TGF-β1 and TGF-β3 with high affinity but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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