Thermo Fisher Scientific PIK3CD Recombinant Rabbit Monoclonal Antibody (JM83-24)
PIK3CD 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. HEK293 세포 발현 시스템에서 생산되었으며, 높은 특이성과 민감도를 제공합니다. 단백질 A로 정제된 액상 제품으로, 장기 보관 시 -20°C에서 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM83-24 |
| Immunogen | Synthetic peptide within Human PI 3 Kinase p110 delta (aa 197–246) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810024 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Protein kinases are enzymes that transfer a phosphate group from a donor molecule, typically the γ-phosphate of ATP, to an acceptor amino acid in a substrate protein. This process mediates most signal transduction in eukaryotic cells, regulating:
- Cellular metabolism
- Transcription
- Cell cycle progression
- Cytoskeletal rearrangement and movement
- Apoptosis and differentiation
The protein kinase family consists of over 500 gene products and is classified into eight major groups based on sequence similarities of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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