Thermo Fisher Scientific c-Rel Recombinant Rabbit Monoclonal Antibody (JM72-93)
c-Rel 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 높은 특이성과 재현성을 제공하며, 로트 간 일관성이 우수함. 단백질 A로 정제된 액상 형태로 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM72-93 |
| Immunogen | Synthetic peptide within Human c-Rel aa 501–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810022 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in these systems. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
The REL gene encodes c-Rel, a transcription factor belonging to the Rel/NFκB family, which also includes RELA, RELB (604758), NFKB1, and NFKB2. These proteins share a conserved N-terminal Rel domain, responsible for DNA binding, dimerization, nuclear localization, and interaction with the NFκB inhibitor (Belguise and Sonenshein, 2007).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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