Thermo Fisher Scientific Axiom Precision Medicine Diversity Array Kit, 96-format

Applied Biosystems™ Axiom™ Precision Medicine Diversity Array Kit, 96-format

The Axiom Precision Medicine Diversity Research Array (PMD Research Array) is a comprehensive, imputation-aware genotyping resource designed to drive deeper scientific insights into complex disease susceptibility, pharmacogenomics (PGx), and genetic factors underlying wellness and lifestyle in diverse populations. It supports population genomics studies with more than 850,000 markers selected for high genomic coverage from the 1000 Genomes Project Phase III. Additional variants were sourced from public databases such as ClinVar, NHGRI-GWAS catalog, CPIC, PharmaGKB, and PharmaADME.

The PMD Research Array is ideal for:

• Bio-banking and longitudinal cohort studies in precision medicine
• Clinical and translational research
• Clinical trials in drug discovery

This kit includes:

• 1×96-format array plate
• Axiom 2.0 Reagents
• Axiom GeneTitan Consumables Kit

For PMD Research Array with Axiom 2.0 Plus reagents, see Cat. No. 951961.

Highlights

• Clinically relevant variants emphasizing ACMG59 genes
• Over 5,000 variants in 1,100+ genes of known PGx value, including CPIC Level A variants
• Blood phenotyping variants for typing and bleeding disorder studies
• Customizable with up to 50,000 additional markers without affecting imputation accuracy

Coverage

• GWAS imputation module with ~800,000 markers across all ancestral populations
• Comprehensive ClinVar and ACMG59 gene coverage
• PGx variants per CPIC and PharmGKB guidelines, including VIP and PharmaADME core variants
• Blood typing variants for rare donor identification and blood disorder studies
• Disease-related variants (e.g., Alzheimer’s, cancer, diabetes, cardiac, neurological disorders)
• Immune-related markers (HLA, KIR, autoimmune, inflammatory)
• Functional variants (loss of function, eQTL, nonsynonymous, lung phenotypes)
• Ancestry, wellness, and lifestyle variants (e.g., pigmentation, caffeine metabolism, cholesterol, obesity)
• Fingerprint and sample tracking markers (mitochondrial and Y chromosome)

Specifications

제품 이미지