Thermo Fisher Scientific Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4)
Human 및 Mouse 시료에 반응하는 재조합 Rabbit Monoclonal 항체로, Tyr783 위치의 phospho-PLCγ1을 특이적으로 인식합니다. Flow Cytometry에 적합하며, 고순도 Protein A/G 정제 및 안정적인 PBS/glycerol buffer로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–1,000 ng/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLCG1Y783-C4 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCγ1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.10% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896961 |
Additional Formats
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes two closely related proteins, PLCγ1 and PLCγ2. These isozymes share core structural domains and possess additional PH, SH2, and SH3 domains. Upon extracellular stimulation by hormones or growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), generating second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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