Thermo Fisher Scientific Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4), APC
Phospho-PLCγ1 (Tyr783)을 인식하는 재조합 토끼 단클론 항체로, APC 형광표지로 유세포분석(Flow Cytometry)에 적합. 인간 및 생쥐 시료 반응성. 고순도 Protein A/G 정제 및 안정적 PBS-BSA 완충액 보존. 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLCG1Y783-C4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCγ1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896964 |
Additional Formats
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes two closely related proteins, PLCγ1 and PLCγ2. These isozymes share core structural domains and possess additional domains, including one PH domain, two SH2 domains, and one SH3 domain. Upon extracellular stimulation by hormones or growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2), generating the second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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