Thermo Fisher Scientific Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4), PE
Phospho-PLCγ1 (Tyr783) 특이적 재조합 Rabbit Monoclonal Antibody로 높은 특이성과 민감도를 제공합니다. PE 형광표지로 유세포분석(Flow Cytometry)에 적합하며, Human 및 Mouse 시료에 반응합니다. 안정적인 로트 간 일관성과 동물유래 성분이 없는 포뮬레이션을 제공합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1x10^6 cells
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLCG1Y783-C4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCγ1 |
| Conjugate | PE |
| Excitation/Emission Max | 565/576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896962 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes PLCγ1 and PLCγ2, which share similar structural domains. PLCγ isozymes contain an additional PH domain, two SH2 domains, and one SH3 domain. Upon stimulation by hormones or growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate second messengers inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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