Thermo Fisher Scientific H3K36me1 Polyclonal Antibody
H3K36me1 단일메틸화 히스톤 H3를 특이적으로 검출하는 폴리클로날 항체입니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 인간 및 마우스 시료에 반응합니다. 고순도 친화 크로마토그래피로 정제되어 연구용으로 적합합니다.
- 카탈로그번호
- PA5114681
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST3H3 (Accession Q16695), corresponding to amino acid residues Q20–T46 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899317 |
Product Specific Information
Antibody detects endogenous levels of Mono-Methyl-Histone H3 only when methylated at Lys36.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can directly alter chromatin structure or facilitate the binding of transcription factors. The N-terminal tail of histone H3 can undergo methylation, acetylation, and phosphorylation, influencing various cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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