Thermo Fisher Scientific Phospho-NR5A1 (Ser203) Polyclonal Antibody
NR5A1 단백질의 Ser203 인산화 형태를 특이적으로 인식하는 rabbit polyclonal 항체. Western blot에 적합하며, 인간, 생쥐, 랫트 반응성. PBS/glycerol buffer에 보관, -20°C 저장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NR5A1 (Accession Q13285), corresponding to amino acid residues around phosphorylated Ser203 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817443 |
Product Specific Information
This antibody detects endogenous levels of Steroidogenic Factor 1 (SF-1) only when phosphorylated at Ser203.
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family and contains two activation function domains (AF1 and AF2). These domains are required for interaction with other nuclear receptors, coactivators, and corepressors such as steroid receptor coactivator-1 (SRC-1), glucocorticoid receptor interacting protein 1 (GRIP1), cAMP response element binding protein (CREB) binding protein (CBP), and silencing mediator of retinoid acid and thyroid hormone receptor (SMRT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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