Thermo Fisher Scientific ATOH1 Monoclonal Antibody (4H2)
ATOH1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4H2). Western blot 및 ELISA에 적합하며, 인간 시료 반응성. 액상 형태로 -20°C 보관, 연구용으로만 사용.
- 카탈로그번호
- H00000474-M09A
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H2 |
| Immunogen | ATOH1 (NP_005163.1, 266–354 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PTPPGSCRTR FSAPASAGGY SVQLDALHFS TFEDSALTAM MAQKNLSPSL PGSILQPVQE ENSKTSPRSH RSDGEFSPHS HYSDSDEAS
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain.
In mice, expression of MATH-1 occurs by embryonic day 9.5 and initially localizes to cranial ganglions and the dorsal part of the central nervous system.
By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in the adult nervous system.
It is suggested that MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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