Thermo Fisher Scientific ATOH1 Monoclonal Antibody (2B1)
ATOH1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합. 인간 시료 반응성, 액상 형태, PBS 버퍼에 보존. 신경세포 분화 연구용으로 활용 가능.
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- H00000474-M13
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B1 |
| Immunogen | ATOH1 (NP_005163, 1–130 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ PPPPPQPPAT LQAREHPVYP PELSLLDSTD PRAWLAPTLQ GICTARAAQY LLHSPELGAS EAAAPRDEVD GRGELVRRSS GGASSSKSPG PVKVREQLCK
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that play an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid HLH transcription factor structurally homologous to the Drosophila proneural gene atonal.
In mice, MATH-1 expression begins by embryonic day 9.5, localizing to cranial ganglions and the dorsal CNS. Expression becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in adult nervous tissue.
MATH-1 may play a role in neural cell differentiation by activating E-box-dependent transcription.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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