Thermo Fisher Scientific SCP2 Monoclonal Antibody (OTI1E4), TrueMAB

Applications

• Western Blot (WB): 1:4,000
• Immunohistochemistry (Paraffin) (IHC (P)): 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), transcribed from two independently regulated promoters.

• The proximal promoter produces the longer SCPx protein.
• The distal promoter produces the shorter SCP2 protein.
  Both share a common C-terminus.

SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids.
SCP2 functions as an intracellular lipid transfer protein.
This gene is highly expressed in organs related to lipid metabolism and may play a role in Zellweger syndrome, characterized by peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing generates multiple transcript variants encoding different isoforms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.