Thermo Fisher Scientific CD52 Monoclonal Antibody (HI186), APC
CD52 단백질을 인식하는 마우스 모노클로날 항체로 APC 형광체가 결합되어 있습니다. 인간 시료에 반응하며 유세포분석(Flow Cytometry)에 적합합니다. 4°C에서 암소 보관하며, 면역세포 표면 단백질 연구에 활용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HI186 |
| Immunogen | Human tonsil |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152314 |
Product Specific Information
This antibody reacts with CD52 (CAMPATH-1), a 21–28 kDa extracellular glycoprotein containing a large N-linked carbohydrate moiety. The mature CD52 molecule is approximately 8–9 kDa. CD52 is expressed at high levels on lymphocytes, monocytes/macrophages, and in the male reproductive tract.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in the regulation of immune responses and is a potential therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders.
CD52 is the target of alemtuzumab, a monoclonal antibody used to treat these conditions by depleting immune cells expressing CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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