
Thermo Fisher Scientific CCR3 Recombinant Superclonal Antibody (23HCLC)
인간 CCR3 단백질을 인식하는 Recombinant Superclonal™ 항체로, 높은 특이성과 민감도를 제공합니다. Expi293 시스템에서 발현된 토끼 IgG 항체이며, 단일 클론의 일관된 재현성을 보장합니다. 면역세포 염색(ICC/IF)에 적합하고, 단백질 A로 정제되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 23HCLC |
| Immunogen | Peptides corresponding to Human CCR3 (aa 337–355, 172–190) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633144 |
Product Specific Information
This antibody is predicted to react with Monkey, Sheep, and Bovine.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency achievable only through recombinant production.
These antibodies recognize multiple epitope sites on the target, enabling higher detection sensitivity for low-abundance targets. Each lot contains an identical known mixture of light and heavy chains, eliminating the biological variability typically associated with polyclonal antibody production.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. It transduces signals by increasing intracellular calcium ion levels and can serve as an alternative co-receptor with CD4 for HIV-1 infection. Chemokines and their receptors play key roles in inflammation and immune cell recruitment, with CCR3 belonging to the CCR subclass of G protein-coupled chemokine receptors.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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