
Thermo Fisher Scientific CD13 Monoclonal Antibody (OTI2E4), TrueMAB
CD13 단백질을 표적하는 Mouse 단일클론 항체로, Western blot 및 IHC(P) 등에 사용 가능. Human 시료 반응성, IgG2a 아이소타입. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로만 사용.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 668–967 of human ANPEP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It acts as a metalloprotease, catalyzing the removal of neutral amino acids from small peptides, thereby regulating bioactive peptide activity.
CD13 is involved in extracellular matrix degradation, antigen processing, and signal transduction, contributing to inflammatory responses, intercellular contact, cell motility, and vascularization.
It is expressed in granulocytes, monocytes, and myeloid leukemia cells, associated with poor carcinoma prognosis, and functions as an aminopeptidase enzyme and alpha receptor for coronavirus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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