Thermo Fisher Scientific CD166 (ALCAM) Monoclonal Antibody (eBioALC48), APC, eBioscience
Flow Cytometry용 CD166(ALCAM) 단클론 항체로, APC 형광체가 결합되어 있습니다. Mouse 시료에 반응하며, 높은 특이성과 재현성을 제공합니다. 0.5 µg/test로 사용 권장, 4°C 암조건 보관. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific CD166 (ALCAM) Monoclonal Antibody (eBioALC48), APC, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested dilution: 0.5 µg/test
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioALC48 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573169 |
Additional Formats
Product Specific Information
Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a 105 kD cell-surface adhesion molecule belonging to the Ig superfamily. It is a type I transmembrane glycoprotein with five extracellular Ig domains, a transmembrane region, and a short cytoplasmic tail. ALCAM mediates homotypic and heterotypic adhesion with its ligand CD6. A soluble isoform inhibits homophilic interactions.
ALCAM is expressed on activated T and B cells, monocyte-derived dendritic cells, and thymic epithelial cells. It is also used as a marker for pluripotent stem cell isolation.
Applications Reported: Suitable for flow cytometric analysis.
Applications Tested: Tested on mouse splenocytes; ≤0.5 µg/test recommended.
Cell number range: 10⁵–10⁸ cells/test. Titrate for optimal performance.
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
The ALCAM (CD166) gene encodes an immunoglobulin receptor subfamily member with five Ig-like domains (VVC2C2C2) in its extracellular domain. It binds to CD6 and plays a role in cell adhesion and migration. Multiple alternatively spliced variants produce different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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