Thermo Fisher Scientific MARCO Recombinant Mouse Monoclonal Antibody (PLK1)
PLK1 클론의 재조합 마우스 단일클론 항체로, 인간 MARCO 단백질을 인식합니다. Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합하며, Protein A로 정제된 액상 형태입니다. 연구용으로 4°C 또는 -20°C 보관 가능합니다.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Frozen) (IHC (F)): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PLK1 |
| Immunogen | The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.
Target Information
MARCO (SR-A6, SCARA2) is a macrophage surface receptor belonging to the class A scavenger receptor family. It binds Gram-negative and Gram-positive bacteria through a C-terminal SRCR domain. The protein includes short cytoplasmic and transmembrane domains, an extracellular spacer, and a long collagenous domain that can form trimeric structures. Due to its expression in tumor-infiltrating macrophages and its immunosuppressive role in the tumor microenvironment, MARCO is considered a potential target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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