Thermo Fisher Scientific p600 Polyclonal Antibody
Thermo Fisher Scientific의 p600 Polyclonal Antibody는 인간 단백질에 반응하는 Rabbit IgG 기반 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적인 결과를 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human retinoblastoma-associated factor 600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
E3 ubiquitin-protein ligase, a component of the N-end rule pathway.
Recognizes and binds proteins with destabilizing N-terminal residues leading to ubiquitination and degradation.
Forms meshwork structures with clathrin involved in membrane morphogenesis and cytoskeletal organization.
Regulates integrin-mediated signaling and may activate FAK in response to cell-matrix interactions.
Mediates ubiquitination of ACLY, leading to its degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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