Thermo Fisher Scientific EDG8 Polyclonal Antibody
Rabbit polyclonal antibody against human EDG8. Validated for Western blot. Supplied as a liquid, unconjugated form at 1 mg/mL. Recommended positive control: RH7777 cells expressing full-length EDG8. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 5–10 µg/mL
- Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of human EDG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074150 |
Product Specific Information
A suggested positive control for this product is RH7777 cells transfected with full-length EDG8 protein.
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular (as a second messenger) and extracellular (as a receptor ligand).
S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors.
Some EDG receptors (e.g., EDG1) are S1P receptors, while others (e.g., EDG2) are LPA receptors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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