Thermo Fisher Scientific Calcineurin A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

Assay-dependent

-

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified peptide conjugated to KLH (a.a. 481-494) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Calcineurin A,uniProtId:Q08209-1,ncbiNodeId:9606,antigenRange:481-494,antigenLength:521,antigenImageFileName:PA1-12404_Calcineurin_A_Q08209-1_Sheep.svg,antigenImageFileNamePDP:PA1-12404_Calcineurin_A_Q08209-1_Sheep_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

0.08% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2169654

Product Specific Information

Peptide sequence: NH2-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-Ser-Asp-Ala-C00H

Target Information

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.