Thermo Fisher Scientific SH3BP2 Polyclonal Antibody
SH3BP2 단백질을 인식하는 Thermo Fisher Scientific의 양친매성 폴리클로날 항체. Western blot에 적합하며, 마우스 시료에 반응. 액상 형태로 제공되며, 1.0 mg/mL 농도. -20°C 보관, 반복 동결·해동은 피해야 함.
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SH2 domain of the 3BP2 protein fused to GST |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2254750 |
Product Specific Information
A suggested positive control for this product is recombinant 3BP2 protein.
Target Information
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain.
It binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, functioning as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells.
Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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