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Thermo Fisher Scientific TIGIT Monoclonal Antibody (MBSA43), Alexa Fluor 700, eBioscience
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Thermo Fisher Scientific

Thermo Fisher Scientific TIGIT Monoclonal Antibody (MBSA43), Alexa Fluor 700, eBioscience

상품 한눈에 보기

인간 TIGIT 단백질을 인식하는 MBSA43 단클론 항체로, Alexa Fluor 700으로 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 5 µL/test로 사용됩니다. 인간 및 붉은털원숭이에 반응하며, 연구용으로만 사용 가능합니다.

카탈로그번호
56-9500-42
브랜드
Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 08. 05. 오전 12:17
Thermo Fisher Scientific 56-9500-42 TIGIT Monoclonal Antibody (MBSA43), Alexa Fluor 700, eBioscience 100 tests pk판매 단위 pk ·
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703,800원VAT 포함 774,180원
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Thermo Fisher Scientific · Thermo Fisher Scientific TIGIT Monoclonal Antibody (MBSA43), Alexa Fluor 700, eBioscience

Applications

Immunohistochemistry (IHC)

Flow Cytometry (Flow)

Product Specifications

항목 내용
Species Reactivity Human
Published Species Not Applicable
Host / Isotype Mouse / IgG1, kappa
Recommended Isotype Control Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Alexa Fluor™ 700, eBioscience™
Class Monoclonal
Type Antibody
Clone MBSA43
Conjugate Alexa Fluor™ 700
Excitation / Emission Max 696 / 719 nm
Form Liquid
Concentration 5 µL/test
Purification Affinity chromatography
Storage Buffer PBS, pH 7.2, with 0.2% BSA
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2815260

Additional Formats

  • Alexa Fluor 488
  • Alexa Fluor 647
  • Alexa Fluor 660
  • APC
  • eFluor 450
  • FITC
  • Functional Grade
  • NovaFluor Red 700
  • PE
  • PE-Cyanine7
  • PE-eFluor 610
  • PerCP-eFluor 710
  • Request custom conjugation

Product Specific Information

The MBSA43 monoclonal antibody reacts with human TIGIT (T cell immunoreceptor with Ig and ITIM domains), also known as VSTM3 or WUCAM. This 26 kDa protein belongs to the poliovirus receptor (PVR) family. TIGIT is expressed on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but not on B cells or naive CD4+ T cells. Expression may be upregulated upon activation.

MBSA43 is reported to cross-react with Rhesus macaque.

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-diluted and tested on normal human peripheral blood cells. Use 5 µL (0.25 µg) per test in 100 µL final volume. Suitable for 10⁵–10⁸ cells/test.

Fluorochrome Information:
Alexa Fluor 700 emits at 723 nm and is excited by the red laser (633–647 nm). Recommended filters: 685 LP mirror and 710/20 band pass filter.

Excitation: 633–647 nm
Emission: 723 nm
Laser: Red Laser

Target Information

TIGIT binds with high affinity to the poliovirus receptor (PVR), leading to increased IL10 and decreased IL12B secretion, thereby suppressing T cell activation and promoting the generation of mature immunoregulatory dendritic cells.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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