Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (GH/3155)
인체 성장호르몬(GH)을 인식하는 단클론 항체로, 뇌하수체 표지자 연구에 적합합니다. IHC(P), IHC(PFA), Peptide Array 등 다양한 실험에 사용 가능합니다. 단백질 A/G로 정제된 액상 항체이며, 방부제 없이 PBS(pH 7.4)에 보관됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GH/3155 |
| Immunogen | Full-length of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17.
These five genes share a high degree of sequence identity, and alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary and acts through membrane receptors belonging to the cytokine receptor subfamily.
Its major role in stimulating body growth is mediated by inducing IGF-1 secretion from the liver and other tissues, promoting differentiation and proliferation of myoblasts, and enhancing amino acid uptake and protein synthesis.
Mutations or deletions in the GH1 gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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