Thermo Fisher Scientific GluR2/GluR3 Recombinant Rabbit Monoclonal Antibody (4K7G5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 400 µg-600 µg extracts of

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4K7G5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 784-883 of human GluR2+GluR3 (P42262). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GluR2/GluR3,uniProtId:P42263-1,ncbiNodeId:9606,antigenRange:784-883,antigenLength:894,antigenImageFileName:MA5-42796_GluR2GluR3_P42263-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42796_GluR2GluR3_P42263-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:GluR2/GluR3,uniProtId:P42262-1,ncbiNodeId:9606,antigenRange:784-883,antigenLength:883,antigenImageFileName:MA5-42796_GluR2GluR3_P42262-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42796_GluR2GluR3_P42262-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.15 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911937

Product Specific Information

Positive test controls include: Mouse brain, Rat brain.

Immunogen sequence: KNKWWYDKGE CGSGGGDSKE KTSALSLSNV AGVFYILVGG LGLAMLVALI EFCYKSRAEA KRMKVAKNAQ NINPSSSQNS QNFATYKEGY NVYGIESVKI

Target Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.