Thermo Fisher Scientific CD5 Monoclonal Antibody (YKIX322.3), APC

Applications

• Flow Cytometry (Flow)

Tested Dilution: Neat
Publications: -

Product Specifications

Additional Formats

• FITC
• Request custom conjugation

Product Specific Information

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Rat anti-Dog CD5 antibody, clone YKIX322.3 recognizes canine CD5, a 67 kDa cell surface type I transmembrane glycoprotein also known as lymphocyte antigen T1, Ly-1 or Leu-1.
CD5 is expressed on the surface of T-cells and thymocytes and at low levels by NK cells (Huang et al. 2008).

Target Information

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein.
It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas.
CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes, mainly in T-cell areas of lymph nodes.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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