Thermo Fisher Scientific TK1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TK1, validated for WB, IHC, and ICC/IF. High purity (>95%) by affinity chromatography. Supplied as unconjugated liquid form, 1 mg/mL concentration. Ideal for research on thymidine kinase-related cellular proce...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human TK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718921 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP
TK1 plays a key role in DNA synthesis and is required for the activity of several antiviral drugs, such as azidothymidine (AZT). It is also utilized in hybridoma selection for monoclonal antibody production. TK1 expression is associated with cell division and has various clinical research applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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