Thermo Fisher Scientific H-cadherin Recombinant Rabbit Monoclonal Antibody (ARC1931)
H-cadherin(CDH13)을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합. 인간, 마우스, 랫트 반응성. HEK293 세포 발현, Affinity chromatography 정제, -20°C 보관. 연구용 한정.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1931 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 101–200 of human Cadherin-13 (CDH13, UniProt ID: P55290) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897972 |
Product Specific Information
- Positive Samples: Mouse heart
- Immunogen sequence:
PHAEDMAELV IVGGKDIQGS LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV DQEPKGIFRI NENTGSVSVT
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, catalyzing the removal of the 3' trailer from precursor tRNAs. It interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1), and reduced expression can suppress TGF-β–induced growth arrest. Mutations in this gene are associated with increased prostate cancer risk. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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