Thermo Fisher Scientific NYX Polyclonal Antibody
Thermo Fisher Scientific의 NYX Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot, IHC, ELISA 등에 사용 가능하며 고순도 친화 크로마토그래피로 정제되었습니다. 안정적인 액상 형태로 연구용에 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 282–481 of human NYX (NP_072089.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.95 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914715 |
Product Specific Information
Positive test controls include: 293T.
The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence:
LLYLDRNSIA FVEEGAFQNL SGLLALHLNG NRLTVLAWVA FQPGFFLGRL FLFRNPWCCD CRLEWLRDWM EGSGRVTDVP CASPGSVAGL DLSQVTFGRS SDGLCVDPEE LNLTTSSPGP SPEPAATTVS RFSSLLSKLL APRVPVEEAA NTTGGLANAS LSDSLSSRGV GGAGRQPWFL LASCLLPSVA QHVVFGLQMD
Target Information
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins.
Defects in this gene cause congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB).
CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus, and reduced visual acuity.
Mutations in this gene disrupt developing retinal interconnections involving ON-bipolar cells, leading to visual losses seen in patients with complete CSNB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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