Thermo Fisher Scientific NYX Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NYX,uniProtId:Q9GZU5-1,ncbiNodeId:9606,antigenRange:282-481,antigenLength:481,antigenImageFileName:PA5-121143_NYX_Q9GZU5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121143_NYX_Q9GZU5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.95 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914715

Product Specific Information

Positive test controls include: 293T. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.

Immunogen sequence: LLYLDRNSIA FVEEGAFQNL SGLLALHLNG NRLTVLAWVA FQPGFFLGRL FLFRNPWCCD CRLEWLRDWM EGSGRVTDVP CASPGSVAGL DLSQVTFGRS SDGLCVDPEE LNLTTSSPGP SPEPAATTVS RFSSLLSKLL APRVPVEEAA NTTGGLANAS LSDSLSSRGV GGAGRQPWFL LASCLLPSVA QHVVFGLQMD

Target Information

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.