Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI5G1), TrueMAB
CDKN2C 단백질을 특이적으로 인식하는 Mouse Monoclonal Antibody. Western Blot에 최적화되어 있으며, 인간 시료에 반응. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 세포주기 조절 및 종양 억제 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G1 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
The CDKN2C gene encodes a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein interacts with CDK4 or CDK6 to prevent kinase activation, thereby regulating cell cycle G1 progression.
Overexpression suppresses cell growth in a manner dependent on RB1 function. Knockout mouse studies indicate its roles in spermatogenesis regulation and tumor suppression. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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