Thermo Fisher Scientific NUMB Monoclonal Antibody (OTI3B2), TrueMAB
NUMB 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화됨. 인간 단백질(aa 1-365) 항원을 기반으로 제작. 동결건조 형태로 제공되며 PBS buffer에 trehalose 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific NUMB Monoclonal Antibody (OTI3B2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–365 of human NUMB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Protein NUMB homolog is an evolutionarily conserved protein involved in neuronal progenitor cell differentiation. It participates in clathrin-dependent endocytosis through interaction with the AP-2 complex. NUMB is expressed in postmitotic neurons and contributes to axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domains exhibit extensive neurite outgrowth, which can be inhibited by VGCC blockers or Ca²⁺ chelators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: CF802164_NUMB_P49757-1_House_mouse.svg, CF802164_NUMB_P49757-1_House_mouse_PDP.jpeg)
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