Thermo Fisher Scientific ICOSLG Monoclonal Antibody (3H8)
Human ICOSLG 단백질을 인식하는 Mouse IgG1 단일클론 항체. ELISA에 적합하며 CD275(B7-H2) 타겟 연구용으로 사용. PBS(pH 7.4) 용액 형태, 보존제 없음. -20°C에서 보관, 동결-해동 반복 피해야 함.
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Applications
- ELISA (ELISA): Tested at 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H8 |
| Immunogen | ICOSLG (AAH64637.1, 18 a.a. ~ 256 a.a.) partial recombinant protein |
| Target Family | CD275 (B7-H2) |
| UniProt ID | O75144-1 |
| Antigen Range | 18–256 |
| Antigen Length | 302 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
ADTQEKEVRA MVGSDVELSC ACPEGSRFDL NDVYVYWQTS ESKTVVTYHI PQNSSLENVD
SRYRNRALMS PAGMLRGDFS LRLFNVTPQD EQKFHCLVLS QSLGFQEVLS VEVTLHVAAN
FSVPVVSAPH SPSQDELTFT CTSINGYPRP NVYWINKTDN SLLDQALQND TVFLNMRGLY
DVVSVLRIAR TPSVNIGCCI ENVLLQQNLT VGSQTGNDIG ERDKITENPV STGEKNAATTarget Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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