Thermo Fisher Scientific ICOSLG Monoclonal Antibody (2D12)
ICOSLG 단백질을 인식하는 마우스 단클론 항체(2D12)로, Human 시료에 반응합니다. Western blot과 ELISA에 적합하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 상태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D12 |
| Immunogen | ICOSLG (AAH64637, 20 a.a. ~ 302 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
TQEKEVRAMV GSDVELSCAC PEGSRFDLND VYVYWQTSES KTVVTYHIPQ NSSLENVDSR
YRNRALMSPA GMLRGDFSLR LFNVTPQDEQ KFHCLVLSQS LGFQEVLSVE VTLHVAANFS
VPVVSAPHSP SQDELTFTCT SINGYPRPNV YWINKTDNSL LDQALQNDTV FLNMRGLYDV
VSVLRIARTP SVNIGCCIEN VLLQQNLTVG SQTGNDIGER DKITENPVST GEKNAATWSI
LAVLCLLVVV AVAIGWVCRD RCLQHSYAGA WAVSPETELT GHVTarget Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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