Thermo Fisher Scientific ICOSLG Monoclonal Antibody (4A11)
Human ICOSLG 단백질을 표적으로 하는 mouse monoclonal antibody (Clone 4A11). Western blot 및 ELISA에 적합하며, PBS buffer에 보존된 액상 형태. 연구용으로 T-cell 활성화 및 cytokine 조절 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A11 |
| Immunogen | ICOSLG (AAH64637.1, 18–135 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ADTQEKEVRA MVGSDVELSC ACPEGSRFDL NDVYVYWQTS ESKTVVTYHI PQNSSLENVD SRYRNRALMS PAGMLRGDFS LRLFNVTPQD EQKFHCLVLS QSLGFQEVLS VEVTLHVA
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: H00023308-M09_CD275_B7-H2_O75144-1_House_mouse.svg, H00023308-M09_CD275_B7-H2_O75144-1_House_mouse_PDP.jpeg)
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