Thermo Fisher Scientific ICOSLG Monoclonal Antibody (4A11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4A11

Immunogen

ICOSLG (AAH64637.1, 18 a.a. approximately 135 a.a) partial recombinant protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD275 (B7-H2),uniProtId:O75144-1,ncbiNodeId:9606,antigenRange:18-135,antigenLength:302,antigenImageFileName:H00023308-M09_CD275_B7-H2_O75144-1_House_mouse.svg,antigenImageFileNamePDP:H00023308-M09_CD275_B7-H2_O75144-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: ADTQEKEVRA MVGSDVELSC ACPEGSRFDL NDVYVYWQTS ESKTVVTYHI PQNSSLENVD SRYRNRALMS PAGMLRGDFS LRLFNVTPQD EQKFHCLVLS QSLGFQEVLS VEVTLHVA

Target Information

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.