Thermo Fisher Scientific UBR2 Monoclonal Antibody (4G4)
UBR2 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4G4). Western blot 및 ELISA에 적합하며, Human 종에 반응. 비보존액성 액체 형태로 -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G4 |
| Immunogen | UBR2 (NP_056070, 1–100 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
MASELEPEVQ AIDRSLLECS AEEIAGKWLQ ATDLTREVYQ HLAHYVPKIY CRGPNPFPQK EDMLAQHVLL GPMEWYLCGE DPAFGFPKLE QANKPSHLCG
Target Information
The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with various proteins, including Eps15, LNX1, and Notch 1.
NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE, or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate.
Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1.
In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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