Thermo Fisher Scientific FBXW11 Monoclonal Antibody (2E7)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

in situ PLA (PLA)

1:1200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2E7

Immunogen

FBXW11 (AAH26213, 1 a.a. approximately 529 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FBXW11,uniProtId:Q9UKB1-1,ncbiNodeId:9606,antigenRange:1-542,antigenLength:542,antigenImageFileName:H00023291-M03_FBXW11_Q9UKB1-1_House_mouse.svg,antigenImageFileNamePDP:H00023291-M03_FBXW11_Q9UKB1-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MEPDSVIEDK TIELMNTSVM EDQNEDESPK KNTLWQISNG TSSVIVSRKR PSEGNYQKEK DLCIKYFDQW SESDQVEFVE HLISRMCHYQ HGHINSYLKP MLQRDFITAL PEQGLDHIAE NILSYLDARS LCAAELVCKE WQRVISEGML WKKLIERMVR TDPLWKGLSE RRGWDQYLFK NRPTDGPPNS FYRSLYPKII QDIETIESNW RCGRHNLQRI QCRSENSKGV YCLQYDDEKI ISGLRDNSIK IWDKTSLECL KVLTGHTGSV LCLQYDERVI VTGSSDSTVR VWDVNTGEVL NTLIHHNEAV LHLRFSNGLM VTCSKDRSIA VWDMASATDI TLRRVLVGHR AAVNVVDFDD KYIVSASGDR TIKVWSTSTC EFVRTLNGHK RGIACLQYRD RLVVSGSSDN TIRLWDIECG ACLRVLEGHE ELVRCIRFDN KRIVSGAYDG KIKVWDLQAA LDPRAPASTL CLRTLVEHSG RVFRLQFDEF QIISSSHDDT ILIWDFLNVP PSAQNETRSP SRTYTYISR

Target Information

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.