Thermo Fisher Scientific CD13 Monoclonal Antibody (WM15)

Applications and Tested Dilution

Product Specifications

Additional Conjugate Formats Available

• Alexa Fluor 488 (MA5-18125)
• APC (MA1-19702)
• FITC (MA1-19703)
• PE (MA1-19704)
• Request custom conjugation

Product Specific Information

The WM15 antibody recognizes an extracellular epitope of the human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells, and myeloid progenitors.

Target Information

CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It functions as a metalloprotease that removes neutral amino acids from small peptides, thereby modulating bioactive peptide activity. CD13 plays roles in extracellular matrix degradation, antigen processing, signal transduction, inflammatory responses, intercellular contact regulation, cell motility, and vascularization. It is expressed by granulocytes, monocytes, and myeloid leukemia cells, with expression linked to poor carcinoma prognosis and protection of leukemic cells against apoptosis. CD13 also serves as an aminopeptidase enzyme and alpha receptor for coronavirus.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.