
Thermo Fisher Scientific CD13 Monoclonal Antibody (WM15)
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Applications
Tested Dilution
Publications
Immunohistochemistry (Frozen) (IHC (F))
Assay-dependent
Flow Cytometry (Flow)
1-4 µg/mL
Immunoprecipitation (IP)
Assay-dependent
Product Specifications
Species Reactivity
Human, Non-human primate
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
WM15
Immunogen
Human AML cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD13,uniProtId:P15144-1,ncbiNodeId:9606,antigenRange:1-967,antigenLength:967,antigenImageFileName:MA1-19359_CD13_P15144-1_House_mouse.svg,antigenImageFileNamePDP:MA1-19359_CD13_P15144-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
View additional formats
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1071214
Product Specific Information
This antibody The antibody WM15 recognizes an extracellular epitope of human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
Target Information
CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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