Thermo Fisher Scientific LGP2 Polyclonal Antibody
LGP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 내재적 LGP2 단백질 검출에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DHX58 (Accession Q96C10), corresponding to amino acid residues N202–K252 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854090 |
Product Specific Information
This antibody detects endogenous levels of total LGP2.
Target Information
Anti-viral innate immune responses are triggered by pathogen-associated molecular patterns such as intracellular nucleic acids resulting from viral infections. Toll-like receptors (TLR3, 7, 8, and 9) are expressed in immune cells and detect foreign nucleic acids as pattern recognition receptors. Other cytoplasmic proteins like RIG-1 and MDA5, members of the CARD-helicase family, play similar roles. LGP2, a related protein lacking a CARD domain, is believed to function as a negative-feedback regulator of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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