Thermo Fisher Scientific GREM2 Polyclonal Antibody
Thermo Fisher Scientific의 GREM2 폴리클로날 항체로, 인간 및 마우스 시료에 반응합니다. Western blot과 IHC(Paraffin)에서 높은 특이성과 재현성을 제공합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: - References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GREM2 (Accession Q9H772), corresponding to amino acid residues A54–F104 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854086 |
Product Specific Information
Antibody detects endogenous levels of total GREM2.
Target Information
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers.
The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.
The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.
As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-106413_GREM2_Q9H772-1_Rabbit.svg, PA5-106413_GREM2_Q9H772-1_Rabbit_PDP.jpeg)
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