Thermo Fisher Scientific IL-4 Monoclonal Antibody (24G2)
Mouse IL-4 단백질을 표적으로 하는 Rat IgG1 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 면역분석에 사용 가능. 비접합 형태이며, 고순도 Protein A 정제 제품으로 LAL 시험을 통해 낮은 엔도톡신 수준 확인됨. 연구용으로만 사용.
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Thermo Fisher Scientific IL-4 Monoclonal Antibody (24G2)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| Flow Cytometry (Flow) | - | 4 publications |
| ELISA | - | 16 publications |
| Neutralization (Neu) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse, Rat |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24G2 |
| Immunogen | Recombinant mouse IL-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_223531 |
Additional Formats
- Biotin conjugate available (Cat. No. MM450DB)
- Custom conjugation service available upon request
Product Specific Information
MM450D targets IL-4 in WB applications and shows reactivity with mouse samples.
The immunogen used is recombinant mouse IL-4.
MM450D detects IL-4, which has a predicted molecular weight of approximately 14 kDa.
This antibody is produced by injecting Rat IgG-secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected and the antibody purified.
Endotoxin level ≤ 10 EU/mg as tested by LAL assay.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and acts as a ligand for the IL-4 receptor.
IL-4 has a broad range of biological functions and shares receptor binding with IL-13, leading to overlapping cytokine activities.
STAT6 is a key transcription factor mediating IL-4 signaling.
The IL-4 gene is located on chromosome 5q within a cytokine gene cluster that includes IL-3, IL-5, IL-13, and CSF2.
IL-4, IL-13, and IL-5 are co-regulated by long-range elements spanning approximately 120 kb.
IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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