Thermo Fisher Scientific SLITRK5 Polyclonal Antibody
SLITRK5 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능하며 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the center of human Slitrk5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153113 |
Product Specific Information
- Suggested positive control: NIH-3T3 cell lysate
- PA5-20477 can be used with blocking peptide PEP-0597
Target Information
SLIT and NTRK-like family 5 (Slitrk5) is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1–6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein.
These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family.
Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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