Thermo Fisher Scientific SLITRK5 Polyclonal Antibody
SLITRK5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능하며 NIH-3T3 lysate를 양성 대조로 권장. 항원 친화 크로마토그래피로 정제된 액상 형태로 1 mg/mL 농도. 신경 및 뇌 조직 연구에 적합.
- 카탈로그번호
- PA520478
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SLITRK5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 2.5 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the center of human Slitrk5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157017 |
Product Specific Information
- Suggested positive control: NIH-3T3 cell lysate
- PA5-20478 can be used with blocking peptide PEP-0598.
Target Information
SLIT and NTRK-like family 5 (Slitrk5) is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1–6). These share two conserved leucine-rich repeat domains in the extracellular region and have significant homology to Slit, a secreted axonal growth-controlling protein.
They are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues but varies within the family.
Overexpression of Slitrk5 inhibits neurite outgrowth in cultured neurons, suggesting involvement in neurite outgrowth regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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