Thermo Fisher Scientific PDCD1/PD1/CD279 (Programmed Cell Death 1) Recombinant Rabbit Monoclonal Antibody (PDCD1/1410R)
PDCD1/PD1/CD279 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 모노클로날 항체입니다. 인간 시료에 반응하며 IHC(P), IHC(PFA)에 사용 가능합니다. 고순도 Protein A/G 정제, 1 mg/mL 농도, PBS(pH 7.4) 저장 버퍼를 사용합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PDCD1/1410R |
| Immunogen | Recombinant human full-length PDCD1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell-mediated immune responses are initiated by T lymphocytes that are stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC). Activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from APCs. PD-1 binds two related ligands, PDL-1 and PDL-2, and upon binding, inhibits immune activation in the absence of danger signals such as LPS. PD1-deficient mice exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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