Thermo Fisher Scientific PDCD1/PD1/CD279 (Programmed Cell Death 1) Polyclonal Antibody
인간 PDCD1/PD1/CD279 단백질을 인식하는 토끼 폴리클로날 항체입니다. 면역조직화학(IHC) 실험에 적합하며, 비결합형 액상 형태로 제공됩니다. Protein A/G로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 5133-RBP7-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PDCD1/PD1/CD279 (Programmed Cell Death 1) Polyclonal Antibody
Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human recombinant PDCD1 protein fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell-mediated immune responses are initiated by T lymphocytes that are stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is self-limited as activated T cells express inhibitory receptors such as PD-1 (PDCD-1).
PD-1 binds two related ligands, PDL-1 and PDL-2, and upon binding, transmits inhibitory signals that suppress immune activation in the absence of danger signals (e.g., LPS).
PD1-deficient mice show hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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