Thermo Fisher Scientific MAP2 Monoclonal Antibody (MT-07)
MAP2 단백질을 인식하는 Thermo Fisher Scientific의 MT-07 단클론 항체. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 돼지 반응성. 단백질 A 정제, 1 mg/mL 농도, PBS 버퍼에 보존. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MT-07 |
| Immunogen | Microtubule protein (bovine brain) enriched for kinesin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076854 |
Product Specific Information
This antibody recognizes an epitope (aa 1375–1395) located in the central domain of Microtubule Associated Protein 2ab (MAP2ab), an intracellular antigen.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a and MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated, and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis.
The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins enriched in dendrites, playing a role in determining and stabilizing dendritic shape during neuron development.
MAP2 is useful in studies of neuron structure in normal and malignant brain tissue, as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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