Thermo Fisher Scientific Caspase 10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Caspase 10 for apoptosis research. Validated in WB and IHC (P) applications. Supplied as unconjugated liquid form with antigen affinity purification. Suitable for use with Jurkat cells as positive control.
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- 500-10854
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human Caspase 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Jurkat Cells
- Cellular location: Cytoplasmic
Target Information
Caspase 10 is a member of the cysteine-aspartic acid protease (caspase) family involved in apoptosis. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing to form active dimers. Caspase 10 cleaves and activates caspases 3 and 7 and is processed by caspase 8. Mutations in this gene are linked to apoptosis defects observed in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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